Next Generation, Modifiable Cardiometabolic Biomarkers: Mitochondrial Adaptation and Metabolic Resilience

Published: October 30, 2023

graphic representing microbes that live on and inside the human body
  • Research advances in multi-omic technologies are broadening our understanding of the molecular mechanisms that underpin metabolic health across the lifespan.
  • ‘Omic’ biomarkers promise to identify the earliest departure from healthy metabolism, which may be very early in life when therapeutic interventions may prove more successful.
  • This statement explores emerging biomarkers of cardiometabolic risk across five interconnected ‘omic’ domains that may serve as leading-edge indicators to detect the earliest departure from healthy metabolism and track returns to healthy metabolism with intervention.