Programming – Vascular Discovery 2026
Hyatt Regency Bellevue | Bellevue, Washington
Vascular Discovery 2026 Schedule-at-a-Glance
| Time | Activity |
|---|---|
| 8:00 a.m. to 6:00 p.m. |
Vascular Research Initiatives Conference (VRIC) Location: Cedar Ballroom |
| 3:00 p.m. to 7:00 p.m. |
Vascular Discovery 2026 Registration Opens On-Site |
| 6:00 p.m. to 8:00 p.m. |
Poster Session 1 & Reception |
| Time | Activity |
|---|---|
| 7:00 a.m. |
Registration Exhibits |
| 7:00 a.m. to 8:00 a.m. |
Continental Breakfast |
| 7:00 a.m. to 8:00 a.m. |
Early Career Training Session 1: Skills for Leadership in Science and Beyond Start your day with an engaging panel discussion focused on developing the leadership skills essential for success in today’s scientific landscape. Leadership is vital at every stage of a scientific career, whether leading a research group, managing industry teams, influencing policy, or building a startup. Our distinguished panelists, representing a range of sectors, will share their leadership journeys, key lessons learned, and practical strategies for becoming an effective and impactful leader. |
| 8:00 a.m. to 8:30 a.m. |
Conference Opening Welcome Moderators: 8:00 Welcome Remarks from American Heart Association's President-Elect 8:15 Welcome Remarks from the Program Chair |
| 8:30 a.m. to 10:00 a.m. |
Plenary Session 1: Hot Topics in Cardiovascular Disease Moderators: 8:30 Talk Title: TBA 9:00 Talk Title: TBA 9:30 Keynote Lecture: TBA |
| 10:00 a.m. to 10:30 a.m. |
Break/Exhibits |
| 10:30 a.m. to 12:00 p.m. |
Concurrent Session 1a: Thrombosis, Hemostasis, and Lymphatic Biology Moderators: 10:30 Talk Title: TBA 10:55 Talk Title: TBA 11:20 VAMP8 Deficiency Attenuates Atherosclerosis Through Impaired Platelet Secretion and Hepatic Lipid Remodeling 11:30 Targeting mitochondrial calcium uniporter attenuates platelet hyperactivation and procoagulant phenotype associated with obesity in humans and mice 11:40 Platelet 12-LOX Mediates the Antiplatelet and Antithrombotic Effects of Omega-3 Eicosapentaenoic Acid and Icosapent Ethyl 11:50 The functional roles of TGF-beta signaling on cardiac lymphangiogenesis during myocardial ischemia |
| 10:30 a.m. to 12:00 p.m. |
Concurrent Session 1b: Peripheral Artery Disease, Aortic Aneurysm, and Cerebrovascular Disease Moderators: 10:30 Talk Title: TBA 10:55 Talk Title: TBA 11:20 Ovariectomy and Chemical Ovarian Failure Exacerbate Atherosclerotic Development without Impairing Ischemic Limb Recovery in Female Mice 11:30 CEPT1 Promotes Peripheral Atherosclerosis Via PLIN2 And Macrophage Recruitment 11:40 Discovery of VS-214, a long-acting apelin agonist, as a first-in-class treatment of peripheral artery disease (PAD) 11:50 Nanoparticle-Mediated PIEZO1 Modulation to Halt Macrophage-Driven PAD Progression Through Targeting PIEZO1-Notch1 Signaling |
| 12:00 to 1:30 p.m. |
PVD Council Annual Business Meeting & Networking Luncheon – OFF SITE Ticket is Required to attend. Purchase ticket here. |
| 12:00 p.m. to 1:30 p.m. | Lunch on your own |
| 1:30 p.m. to 3:00 p.m. |
Plenary Session 2: Highlights from the ATVB Journal Moderators: 1:30 Daniel Steinberg Early Career Investigator Award in Atherosclerosis/Lipoproteins: 1:45 Karl Link Early Career Investigator Award in Thrombosis 2:00 Werner Risau Early Career Investigator Award in Vascular Biology 2:15 David A Dichek Mid-Career Investigator Award Lecture 2:35 ATVB Journal Report |
| 3:00 p.m. to 3:30 p.m. |
Break/Exhibits |
| 3:30 p.m. to 5:00 p.m. |
Concurrent Session 2a: Shobha Ghosh Investigator in Training Award Competition &
Newly Released 2026 Guideline for the Evaluation and Management of Acute Pulmonary Embolism in Adults Moderators: Shobha Ghosh Investigator in Training Award Competition 3:30 Single-Nuclei Transcriptomics Reveals Divergent Regenerative Trajectories and Signaling Networks in Response to Exercise Therapy in Peripheral Artery Disease 3:45 Primary Cilia Protein IFT88 Is a Key Governor of Smooth Muscle Phenotype 4:00 Lipid Nanoparticle-based Delivery of Sting siRNA for In Vivo Silencing of STING in Aorta to Alleviate Aortic Aneurysm and Dissection 4:15 Microvascular Impairment Drives Diastolic Dysfunction in a three-hit mouse model of Heart Failure with Preserved Ejection Fraction Newly Released 2026 Guideline for the Evaluation and Management of Acute Pulmonary Embolism in Adults 4:30-5:00 TBA |
| 3:30 p.m. to 5:00 p.m. |
Concurrent Session 2b: Immunology and Inflammation in Vascular Disease Moderators: 3:30 Talk Title: TBA 3:55 Talk Title: TBA 4:20 Macrophage-Targeted Oxygen-Generating Theranostic Photoactivation Facilitates Inflammation Resolution and Stabilization of Hypoxic Atherosclerotic Plaques 4:30 TBD 4:40 V-domain Immunoglobulin Suppressor of T cell Activation (VISTA) is protective against atherosclerosis 4:50 Macrophage-Targeted Oxygen-Generating Theranostic Photoactivation Facilitates Inflammation Resolution and Stabilization of Hypoxic Atherosclerotic Plaques |
| 5:00 p.m. to 7:00 p.m. |
Poster Session 2 & Reception – Sponsored by the ATVB Journal |
| Time | Activity |
|---|---|
| 7:00 a.m. |
Registration Exhibits |
| 7:00 a.m. to 8:00 a.m. |
Continental Breakfast |
| 7:00 a.m. to 8:00 a.m. |
Early Career Training Session 2: Roundtable Events Kick off your morning with our engaging and interactive roundtable events, a dynamic and interactive session designed to facilitate small-group discussions on key topics essential for career development. Each roundtable will provide a space to ask questions, share experiences, and gain valuable insights from seasoned professionals. This session is open to all attendees but specifically targeted towards early career/student trainee attendees. |
| 8:00 a.m. to 9:30 a.m. |
Plenary Session 3: Advancing Cardiometabolic Care: From GLP-1 to SGLT2 and Beyond Moderators: 8:00 Title TBA 8:30 Title TBA 9:00 Title TBA |
| 9:30 a.m. to 10:00 a.m. |
Break/Exhibits |
| 10:00 a.m. to 11:30 a.m. |
Concurrent Session 3a: Metabolic Disorders and Vascular Diseases Moderators: 10:00 Talk Title: TBA 10:00 Talk Title: TBA 10:25 Talk Title: TBA 10:50 Macrophage full-length TREM2 suppresses hepatic apolipoprotein C3 secretion and atherosclerosis in prediabetic hepatic steatosis 11:00 Dual Inhibition of Sodium-Glucose Cotransporters 1 and 2 Attenuates Atherosclerosis via Metabolic Reprogramming Toward Fatty Acid Oxidation 11:10 Sex-specific multi-omics analysis of metabolic and molecular crosstalk between MASH and atherosclerosis 11:20 Extracellular vesicles produced by human β -cells exposed to T1D related inflammatory stress cytokines communicate impaired immunometabolic signaling to macrophages and CD4+ T lymphocytes |
| 10:00 a.m. to 11:30 a.m. |
Concurrent Session 3b: Vessel Wall Biology and Smooth Muscle Cell Dysfunction Moderators: 10:00 Talk Title: TBA 10:25 Talk Title: TBA 10:50 Dedicated Smooth Muscle Progenitor Populations, Marked by Notch3 and Sox9, Show Distinct Atherosclerotic Plaque Fate 11:00 Endothelial AGO1 Drives Vascular Inflammation, Hyperlipidemia, and Atherosclerosis via a Non-Canonical Nuclear Mechanism 11:10 Integrated single-cell and spatial transcriptomics identify DLX6-AS1 as a driver of smooth muscle cell transition in human atherosclerosis 11:20 Metabolic changes influence vascular smooth muscle cell differentiation state |
| 11:30 a.m. to 1:00 p.m. |
The Mentor of Women Award Luncheon - The Career Ladder Negotiation: How to Ask for What You Need at Every Step Whether you are a PhD candidate, a physician-scientist finalizing your first faculty offer, or a seasoned Professor navigating complex leadership roles, negotiation is one of the most critical “soft skills” in your academic toolkit. This session moves beyond simply “asking for more” and focuses on mastering the art of collaborative problem-solving within the unique culture and constraints of academia. |
| 11:30 a.m. to 1:00 p.m. | Lunch on your own |
| 1:00 p.m. to 3:00 p.m. |
Plenary Session 4: Early Career Investigator Award Competition: Moderators: Irvine H. Page Junior Faculty Research Award Competition 1:00 Leucine-Dependent mTORC1 Signaling in Macrophages Mediates the Divergent Atherogenic Risks of Animal and Plant Proteins 1:15 The Interleukin Signaling in Atherogenic Endothelial Reprogramming 1:30 Defective Lymphatic Drainage and Junctional Disorganization Impair Cardiac Injury Resolution After Myocardial Infarction 1:45 Nestin+ macrophages engage IGF-1 signaling required for atherosclerosis regression Kenneth M. Brinkhous Early Career Investigator Prize in Thrombosis Competition 2:00 A Peroxiredoxin-like Oxidation Mechanism on Protein Disulfide Isomerase Promotes Thrombosis in Oxidative Stress 2:15 A molecular hotspot oppositely regulates platelet adhesion and aggregation to differentiate thrombosis and hemostasis 2:30 The Repurposing of FDA-Approved Hypoxia-Inducible Factor 1 Agonists is an Alternative Therapeutic Option for Deep Vein Thrombosis 2:45 Mechanisms of Thrombosis in Fibromuscular Dysplasia |
| 3:00 p.m. to 3:30 p.m. | Break/Exhibits Location: |
| 3:30 p.m. to 5:00 p.m. |
Concurrent Session 4a: Lipid Metabolism and Novel Therapeutic Targets in Atherosclerosis
Moderators: 3:30 Talk Title: TBA 3:55 Talk Title: TBA 4:20 Lipoproteins are susceptible to proteolytic modifications that may alter their atherogenicity 4:30 Phosphatidylcholine Acyl Chain Composition Determines the Directionality of Lipid Transfer Between Nanoparticles and HDL 4:40 PIP2 metabolism as a novel therapeutic target for reverse cholesterol transport and atherosclerosis 4:50 Lipoprotein(a) undergoes Endothelial Transcytosis via Activin receptor-Like Kinase 1: An Unexpected Mechanism for Residual Cardiovascular Risk |
| 3:30 p.m. to 5:00 p.m. |
Concurrent Session 4b: Genomics, Epigenetics, and Precision Medicine in Vascular Disease Moderators: 3:30 Talk Title: TBA 3:55 Talk Title: TBA 4:20 Genetically Decreased CPS1 Activity Attenuates Risk of Coronary Artery Disease in Humans and Atherosclerosis in Mice Through Sexually Dimorphic Patterns 4:30 Systematic Mapping of Smooth Muscle Cell Gene Programs That Drive Genetic Risk for Coronary Artery Disease 4:40 A Single-Cell and Spatial Transcriptomic Atlas of Human Pulmonary Arterial Hypertension 4:50 Stage dependent transcriptomic profiling identifies Syndecan-2 dysregulation during neural crest derived smooth muscle differentiation in smooth muscle dysfunction syndrome |
| 5:00 p.m. to 7:00 p.m. | Poster Session 3 & Reception Location: Grand Ballroom |
| 7:00 p.m. to 10:00 p.m. |
Vascular Discovery Council Celebration – OFF SITE Ticket is Required to attend. Visit the Registration Desk onsite for more information or purchase ticket here. |
| Time | Activity |
|---|---|
| 7:30 a.m. | Registration Location: Regency Foyer |
| 7:30 a.m. to 8:30 a.m. | Continental Breakfast Location: Evergreen Foyer |
| 7:30 a.m. to 8:30 a.m. |
Inside the American Heart Association's Research Enterprise: Grant Funding and Other Opportunities Jessica M. Biddinger, American Heart Association |
| 8:30 a.m. to 9:00 a.m. | Plenary Session 5: Council Awards and Recognition Location: Evergreen Ballroom |
| 9:00 a.m. to 9:30 a.m. | Break Location: Evergreen Foyer |
| 9:30 a.m. to 11:00 a.m. |
Plenary Session 6: Invited Lecture Series Moderators: 9:30 Vascular Discovery Distinguished Lecture: TBA 10:00 Jeffrey M. Hoeg Arteriosclerosis, Thrombosis, and Vascular Biology Award for Basic Science and Clinical Research—Sponsored by the Council on Arteriosclerosis, Thrombosis, and Vascular Biology: 10:30 PVD Mid-Career Award & Lecture –Sponsored by Council on Peripheral Vascular Disease: |
| 11:00 a.m. to 11:15 a.m. |
Closing Remarks |
About this Meeting
This 2 ½-day meeting is sponsored by the Council on Arteriosclerosis, Thrombosis and Vascular Biology, the Peripheral Vascular Disease Council, and the Council on Genomic and Precision Medicine, in cooperation with and the Society for Vascular Surgery's Vascular Research Initiatives Conference.
Vascular Discovery Scientific Sessions will provide unique opportunities to meet with colleagues from around the world with wide-ranging research interests and expertise for the timely exchange of information about new and emerging scientific research in the areas of arteriosclerosis, thrombosis and vascular biology, peripheral vascular disease, vascular surgery research, genomics and precision medicine. We expect a broad representation from many disciplines and encourage young scientists to attend.
See the American Heart Association Policies and Guiding Values (PDF).
Target Audience
The conference will especially appeal to scientists and clinicians interested in:
- Allergy and Immunology
- Arteriosclerosis
- Biochemistry
- Biological Sciences
- Diabetes and Metabolism
- Functional Genomics
- Genetics
- Hematology
- Internal Medicine
- Molecular/Cellular Biology
- Nutrition
- Pathology
- Peripheral Artery Disease
- Pharmacology
- Physiology
- Vascular Surgery
- Thrombosis
- Vascular Biology
- Vascular Medicine
Learning Objectives
At the conclusion of this conference, participants will be able to:
- Discuss recent advances and emerging experimental models in ATVB and peripheral vascular diseases that target primary acquired diseases and/or secondary factors contributing to vascular-related disorders.
- Summarize findings from recent translational research or clinical trials and the impact for future treatment and/or management of vascular-related disorders.
- Describe best practices associated with ATVB scientific research and/or the management of patients with vascular-related diseases.